Live-Cell Nuclear Labeling
Nuclear staining is crucial to cell biology research for precise measurements of cell count, proliferation, or image segmentation.
Current methods, like engineered cell lines or toxic dyes limit the information that can be gleaned from cell imaging assays. Saguaro's non-toxic nuclear dye finally makes it possible to perform long-term live-cell imaging without perturbing cells, and without the need to perform lentiviral transduction.
NucleoLIVE™ Features
Opening up new possibilities for cell imaging studies
Non-Toxic
Unperturbed cells in week-long assays
Mix-and-Read
One-step, no-wash dye which remains in media throughout the assay.
Robust staining
High-quality staining of nuclei retained over time, with constant labeling of cells as they divide.
Applications
Catch New Kinetic Insights
Cell Counting
Accurately quantify cell toxicity, viability, and morphology
Long-term assays
Generate growth curves to quantify drug effects on cell proliferation in real time and over multiple days
Biocompatible cell segmentation
Simplify image analysis in live cells by using a nuclear stain for cell segmentation
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NucleoLIVE FAQ
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Saguaro's Non-toxic Nuclear Dye is excited at 561nm with standard yellow emission
