More Live-Cell Dyes
Non-Toxic Dyes for Live-Cell Imaging
Capture new biological insights at scale
It's not about moving into live-cell assays.
It's about enriching insights, and simplifying your assays.
● ChromaLIVE™ Non-Toxic Dye
Pushing beyond the limits of cell painting: better insights, easier workflows.
Testimonials
“ChromaLIVE™ has completely transformed our cell screening workflows. Its non-toxic, wash-free protocol gives similar data to cell painting, but with additional insights[...] This new tool has allowed us to identify novel hits and mechanistic insights from prior campaigns.”
Dr. Simon Mathien
HTS Platform Lead Institute for Research in Immunology and Cancer at IRIC
“The unbiased, data-rich insights provided by ChromaLIVE™ have been a game-changer in stratifying CLL patient cohorts[...] allowing us to identify new patient cohorts with predictable drug responses, something not possible with conventional clinical criteria or traditional in vitro assays.”
Dr. David Andrews
Director of and senior scientist in Biological Sciences at Sunnybrook Research Institute
“After testing the Saguaro dyes, we immediately saw the value in changing how we screen drugs in our 3D organoid systems[...] NucleoLIVE™, MortaLIVE™ and ChromaLIVE™ showed superior penetration, enabling clear visualization of cells in the organoid core, critical for monitoring cell death and effects of hypoxia.”
Dr. Magnar Bjørås
Professor of Medicine at NTNU
ChromaLIVE™: the leading technology for profiling drugs with images
Non-Toxic
With unaffected gene expression, cells remain unperturbed with ChromaLIVE™, providing the most accurate biological data. Perfect for the most sensitive cells like iPSC and organoids in long-term cultures.
Live Cell Painting
ChromaLIVE™ is a data-rich dye, providing high-density cell information to enrich HIT detection, and more accurately profile cell responses in high-throughput screening.
Mix-and-Read
No wash, no fixation, no plate copies. It's easy to use ChromaLIVE™ in high-throughput assays: a one-step, mix-and-read dye.
● NucleoLIVE™ Non-Toxic Dye
A non-toxic nuclear dye providing new cell proliferation data
Go beyond tedious transfections or endpoint cell viability assays based on ATP detection, and open the door to new cell proliferation data in both 2D and 3D assays.
● MortaLIVE™ Non-Toxic Dye
Live-dead assays made easier and more insightful
Go beyond ATP measurements like CellTiter-Glo assays. Get enriched cell health insights in high-troughput.
● ER-LIVE™ Non-Toxic Dye
Track ER dynamics over time without perturbing cells
Unsurpassed in staining quality and in preserving cell physiology. Enhance your endoplasmic reticulum studies and capture new time-sensitive insights.
Frequently Asked Questions
-
Saguaro ships direct to customers everywhere in the world. It relies on Funakoshi in Japan, and Chayon Laboratories in South Korea.
-
Yes. Saguaro offers drug testing experiments, and leverages its reference dataset of 3000+ annotated compounds stained with ChromaLIVE, the leading technology for profiling drugs with images of cells. We use our Yokogawa CQ1 high-content imaging system, connected to an automation platform for high-throughput screening.
We also help with image and data analysis. Contact us to learn more!
-
Non-toxic dyes, and drug profiling as a service.
Products: Saguaro mainly offers three non-toxic and data-rich dyes: ChromaLIVE™, which also comes in a different color and is called ChromaLIVE™ Deep Red, NucleoLIVE™, and MortaLIVE™. We set a new standard for absence of toxicity and the high-density of relevant biological information they provide. We only commercialize dyes that are biologically inert for at least 3 days in cell culture, and from the design phase, we insist on dyes that will provide the richest staining possible.
Service: We leverage our industry-leading expertise in live-cell imaging screens to offer a drug profiling service, where our customers' compounds are profiled against a reference dataset of 3000 well-annotated compounds. We leverage ChromaLIVE™, which goes beyond fixed cell painting and has made its place as the leading technology for profiling drugs with cell images.
Interested in our live cell dyes?
Join the 150+ biotech and pharma companies using Saguaro's non-toxic dyes for new insights
