More Live-Cell Dyes
Non-Toxic Dyes for Live-Cell Imaging
Capture new biological insights at scale
ChromaLIVE™ Non-Toxic Dye
A data-rich dye for live-cell phenotypic profiling
● ChromaLIVE™
Go beyond the limits of cell painting to profile drugs in high-content imaging
ChromaLIVE™: differentiate cell phenotypes like never before
Non-Toxic
With unaffected gene expression, ChromaLIVE can be used with sensitive cells like iPSCs or organoids over weeks to capture subtle cellular responses
Live Cell Painting
The leading technology for image-based profiling, ChromaLIVE sensitively detects bioactivity and accurately profiles cell responses to hint at drug mechanism
Mix-and-Read
It's easy to use ChromaLive in high-throughput assays: a one-step, mix-and-read dye that does not require any wash step
● NucleoLIVE™ Non-Toxic Dye
A non-toxic nuclear dye providing new cell proliferation data
Go beyond tedious transfections or endpoint cell viability assays based on ATP detection, and open the door to new cell viability data in high-throughput screens
● MortaLIVE™ Non-Toxic Dye
Live-dead assays made easier and more insightful
Mix-and-read assay to easily study cell viability and cytotoxicity in real time over multiple days
Frequently Asked Questions
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Saguaro ships direct to customers everywhere in the world. It relies on Funakoshi in Japan, and Chayon Laboratories in South Korea.
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Yes. Saguaro offers drug testing experiments, and leverages its reference dataset of 3000+ annotated compounds stained with ChromaLIVE, the leading technology for profiling drugs with images of cells. We use our Yokogawa CQ1 high-content imaging system, connected to an automation platform for high-throughput screening.
We also help with image and data analysis. Contact us to learn more!
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Non-toxic dyes, and drug profiling as a service.
Products: Saguaro mainly offers three non-toxic and data-rich dyes: ChromaLIVE™, which also comes in a different color and is called ChromaLIVE™ Deep Red, NucleoLIVE™, and MortaLIVE™. We set a new standard for absence of toxicity and the high-density of relevant biological information they provide. We only commercialize dyes that are biologically inert for at least 3 days in cell culture, and from the design phase, we insist on dyes that will provide the richest staining possible.
Service: We leverage our industry-leading expertise in live-cell imaging screens to offer a drug profiling service, where our customers' compounds are profiled against a reference dataset of 3000 well-annotated compounds. We leverage ChromaLIVE™, which goes beyond fixed cell painting and has made its place as the leading technology for profiling drugs with cell images.
Interested in our live cell dyes?
Join the 150+ biotech and pharma companies using Saguaro's non-toxic dyes for new insights
Testimonials
“ChromaLIVE™ has completely transformed our cell screening workflows. Its non-toxic, wash-free protocol gives similar data to cell painting, but with additional insights[...] This new tool has allowed us to identify novel hits and mechanistic insights from prior campaigns.”
Dr. Simon Mathien
HTS Platform Lead Institute for Research in Immunology and Cancer at IRIC
“The unbiased, data-rich insights provided by ChromaLIVE™ have been a game-changer in stratifying CLL patient cohorts[...] allowing us to identify new patient cohorts with predictable drug responses, something not possible with conventional clinical criteria or traditional in vitro assays.”
Dr. David Andrews
Director of and senior scientist in Biological Sciences at Sunnybrook Research Institute
“After testing the Saguaro dyes, we immediately saw the value in changing how we screen drugs in our 3D organoid systems[...] NucleoLIVE™, MortaLIVE™ and ChromaLIVE™ showed superior penetration, enabling clear visualization of cells in the organoid core, critical for monitoring cell death and effects of hypoxia.”
Dr. Magnar Bjørås
Professor of Medicine at NTNU